Lifestyle-related risk factors for Parkinson's disease: a population-based study (2024)

Lifestyle-related risk factors for Parkinson's disease: a population-based study (1) https://doi.org/10.1034/j.1600-0404.2003.00128.x · Lifestyle-related risk factors for Parkinson's disease: a population-based study (2)

Journal: Acta Neurologica Scandinavica, 2003, №4, p.239-244

Publisher: Hindawi Limited

Authors:

  1. M. Baldereschi
  2. A. Di Carlo
  3. P. Vanni
  4. A. Ghetti
  5. P. Carbonin
  6. L. Amaducci
  7. D. Inzitari
  8. for the Italian Longitudinal Study on Aging Working Group

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About this publication

Number of citations 43
Number of works in the list of references 36
Journal indexed in Scopus Yes
Journal indexed in Web of Science Yes
Lifestyle-related risk factors for Parkinson's disease: a population-based study (2024)

FAQs

What lifestyle risk factors cause Parkinsons? ›

Lifestyle factors including physical activity, alcohol and caffein consumption, and smoking habit are important in that they are modifiable and can affect PD onset and progression. Several previous studies have reported the association between lifestyle factors and the incidence, progression, and mortality of PD.

What population is most at risk for Parkinson's disease? ›

The disease usually occurs in older people, but younger people can also be affected. Men are affected more often than women. The cause of PD is unknown but people with a family history of the disease have a higher risk. Exposure to air pollution, pesticides and solvents may increase risk.

What are the possible factors that may increase the risk for Parkinson's disease? ›

Medical experts believe that environmental causes may help trigger Parkinson's disease. Exposure to farming chemicals, like pesticides and herbicides; Vietnam-era exposure to Agent Orange; and working with heavy metals, detergents and solvents have all been implicated and studied for a clearer link.

What is denial in Parkinson's disease? ›

Denial, Disbelief, Shock

Denial can be a useful coping mechanism if it allows you to largely ignore symptoms and go on with life as usual. However, if denial leads to the refusal to take medication or going to extremes seeking multiple second opinions, it may indicate denial as an unhealthy response.

What is the main cause of Parkinson's disease? ›

Parkinson's disease is a progressive disorder that is caused by degeneration of nerve cells in the part of the brain called the substantia nigra, which controls movement. These nerve cells die or become impaired, losing the ability to produce an important chemical called dopamine.

What are the genetic risk factors for Parkinson's? ›

About 15 percent of people with Parkinson's disease have a family history of the condition, and family-linked cases can result from genetic mutations in a group of genes — LRRK2, PARK2, PARK7, PINK1 or the SNCA gene (see below).

Who is at high risk for Parkinson's? ›

It ordinarily begins in middle or late life, and the risk increases with age. People usually develop the disease around age 60 or older. If a young person does have Parkinson's disease, genetic counseling might be helpful in making family planning decisions.

What is the new cause of Parkinson's disease? ›

Degeneration of dopaminergic neurons is widely accepted as the first event that leads to Parkinson's. But the new study suggests that a dysfunction in the neuron's synapses — the tiny gap across which a neuron can send an impulse to another neuron — leads to deficits in dopamine and precedes the neurodegeneration.

What race is most at risk for Parkinson's disease? ›

Some studies suggest that Parkinson's is more prevalent in White populations. Whilst it's possible that environmental factors (such as diet) or genetic factors are partly responsible for this, it can be hard to compare data from different countries because the studies are often carried out in very different ways.

Who is most likely to be affected by Parkinson's disease? ›

Following Alzheimer's disease, Parkinson's disease (PD) is the second-most common neurodegenerative disorder in the United States. Most people diagnosed with PD are age 60 years or older, however, an estimated 5 to 10 percent of people with PD are diagnosed before the age of 50.

Which individual would be most at risk for developing Parkinson's disease (PD)? ›

Risk factors for PD include: Age—The average age of onset is about 70 years, and the incidence rises significantly with older age. However, a small percent of people with PD have “early-onset” disease that begins before the age of 50. Biological sex—PD affects more men than women.

Which area is most likely to cause Parkinson's disease? ›

Parkinson's disease is caused by a loss of nerve cells in the part of the brain called the substantia nigra. Nerve cells in this part of the brain are responsible for producing a chemical called dopamine.

What is the red flag for Parkinson? ›

Some of the red flags discussed are asymmetry (where symptoms such as slowness, stiffness, and tremor usually start on one side of the body) and slow progression of symptoms. They also describe how some patients may have symptoms that mimic Parkinson's, but is not Parkinson's.

What famous singer has Parkinson's disease? ›

Linda Ronstadt: Parkinson's Took Her Voice But Not Her Spirit. Known for her rich soprano vocals as the lead singer of the 1960s band the Stone Poneys, Linda Ronstadt opened up about her Parkinson's disease diagnosis to AARP The Magazine in 2013.

What food is not good for Parkinson's? ›

Lastly, it's recommended to limit or avoid processed foods, such as canned foods, fried foods, and regular and diet sodas, as these have been linked to a more rapid progression of Parkinson's ( 37 ). Processed foods may also impair gut health, which may affect symptom severity ( 38 ).

What environmental factors can cause Parkinson's disease? ›

Pesticides and Other Harmful Chemicals Linked to Parkinson's

In addition to air pollution, Dorsey identifies two types of chemicals that have been strongly linked to Parkinson's: pesticides like paraquat, and cleaning chemicals like trichloroethylene (TCE).

Can stress cause Parkinson's disease? ›

Research suggests that stressful life events may increase the risk of Parkinson's disease. In addition, animal studies indicate that stress damages dopamine cells, resulting in more severe parkinsonian symptoms. In humans, acute stress can worsen motor symptoms, including bradykinesia, freezing, and tremor.

References

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